PCSK6 exacerbates Alzheimer's disease pathogenesis by promoting MT5-MMP maturation

ARG10112: WB / Human, Mouse

Mingliang Xu et al.
Exp Neurol.,  (2024)

Biochanin A inhibits cardiac hypertrophy and fibrosis in vivo and in vitro

ARG10112: WB / Mouse, Rat

Zhenyu Feng et al.
Biomed Pharmacother.,  (2024)

Shionone relieves oxygen-glucose deprivation/reoxygenation induced SH-SY5Y cells injury by inhibiting the p38 MAPK/NF-κB pathway

ARG10112: WB / Human

Xiaoli Zhou et al.
J Cardiothorac Surg,  (2024)

7,8-Dihydroxyflavone ameliorates cognitive impairment induced by repeated neonatal sevoflurane exposures in mice through increasing tau O-GlcNAcylation

ARG10112: WB / Mouse

Mingliang Xu et al.
Neurosci Lett.,  (2024)

The effect of long-term administration of green tea catechins on aging-related cardiac diastolic dysfunction and decline of troponin I

ARG10112: WB / Mouse

Junjun Quan et al.
pre-print,  (2024)

Discovery of the First Subnanomolar PPARα/δ Dual Agonist for the Treatment of Cholestatic Liver Diseases

ARG10112: WB / Mouse

Zhiqi Feng et al.
J Med Chem.,  (2023)

Knockdown of Porf-2 restores visual function after optic nerve crush injury

ARG10112: WB / Mouse

Di Chen et al.
Cell Death Dis.,  (2023)

Resveratrol inhibits Toxoplasma gondii-induced lung injury, inflammatory cascade and evidences of its mechanism of action

ARG10112: WB / Mouse

Yu Nan Lu et al.
Phytomedicine.,  (2023)

KDF1 Promoted Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells through Activating STAT3 and AKT Pathway

ARG65350: WB / 

Yi-Qing Guo et al.
Biomedicines.,  (2023)

Uric acid mitigates cognitive deficits via transcription factor EB - mediated microglial autophagy in mice models of Alzheimer's disease

ARG10112: WB / Mouse

Qian Xiao et al.
,  (2023)

黄芪甲苷预处理对大鼠肠缺血再灌注所致肺损伤的影响及其机制

ARG10112: WB / Rat

王蕾 et al.
中国中西医结合外科杂志,  (2023)

PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis

ARG10112: WB / Rat

Xiang Xue et al.
J Orthop Surg Res.,  (2023)

Lack of interferon regulatory factor 3 leads to anxiety/depression-like behaviors through disrupting the balance of neuronal excitation and inhibition in mice

ARG10112: WB / Mouse

Junjie Li et al.
Genes & Diseases,  (2022)

Genetic labeling reveals cellular expression pattern of neuregulin 1 in mouse forebrain

ARG10112: WB / Human

Chen-Yun Ding et al.
Research square,  (2022)

Downregulation of lncRNA NEAT1 alleviates sepsis-induced acute kidney injury

ARG10112: WB / Human

Yuhua Zhou et al.
Cent Eur J Immunol .,  (2022)

Qi-Tai-Suan, an oleanolic acid derivative, ameliorates ischemic heart failure via suppression of cardiac apoptosis, inflammation and fibrosis

ARG10112: WB / Human

QIAN Ming et al.
 Chinese Journal of Natural Medicines ,  (2022)

Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation

ARG65681: IHC-P / Mouse

Zhenyu Tian et al.
Cell Host Microbe,  (2022)

SCM-198 Prevents Endometriosis By Reversing Low Autophagy Levels Of Endometriotic Stromal Cells Via Inhibiting TNF-Α-Aromatase-Estrogen-Erα Pathway And Promoting PR Expression

ARG10122: WB / Human

Yikong Lin et al.
Research Square,  (2022)

SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals

ARG10112: WB / Mouse

Yi-Kong Lin  et al.
Front Endocrinol (Lausanne),  (2022)

Pharmacological inhibition of SMYD2 protects against cisplatin-induced acute kidney injury in mice

ARG10112: WB / Mouse

Binbin Cui  et al.
Front Pharmacol,  (2022)

Mesenchymal Stem Cells-Derived Exosomes Ameliorate Ischemia/Reperfusion Induced Acute Kidney Injury in a Porcine Model

ARG10112: WB / Pig

Jianni Huang et al.
Frontiers in Cell and Developmental Biology,  (2022)

Design, Synthesis, and Activity Evaluation of Novel Acyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo.

ARG65350: WB / Mouse

Er-Jun Hao et al.
J Med Chem.,  (2021)

Blocking the CCL5-CCR5 Axis Using Maraviroc Promotes M1 Polarization of Macrophages Cocultured with Irradiated Hepatoma Cells.

ARG65350: WB / Mouse

Yuan Zhuang et al.
J Hepatocell Carcinoma.,  (2021)

Intermittent pressure imitating rolling manipulation ameliorates injury in skeletal muscle cells through oxidative stress and lipid metabolism signalling pathways.

ARG65350: WB / Mouse

Li-Juan Zhao et al.
Gene.,  (2021)

Repurposing the FDA-approved anticancer agent ponatinib as a fluconazole potentiator by suppression of multidrug efflux and Pma1 expression in a broad spectrum of yeast species.

ARG65350: WB / Mouse

Lin Liu et al.
Microb Biotechnol.,  (2021)

Structural Basis of VSIG3: The Ligand for VISTA.

ARG10112: WB / Human

Xiaoxue Xie et al.
Front Immunol.,  (2021)

The Phosphorylation Status of Drp1-Ser637 by PKA in Mitochondrial Fission Modulates Mitophagy via PINK1/Parkin to Exert Multipolar Spindles Assembly during Mitosis.

ARG10112: WB / Human

Huey-Jiun Ko et al.
Biomolecules.,  (2021)

Mesenchymal Stem Cell-Derived Exosomes Ameliorate Alzheimer's Disease Pathology and Improve Cognitive Deficits.

ARG10112: WB / Human

Yi-An Chen et al.
Biomedicines.,  (2021)

Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid

ARG10112: WB / Human

Liu Liu et al.
Eur J Med Chem .,  (2021)

M351-0056 is a novel low MW compound modulating the actions of the immune-checkpoint protein VISTA.

ARG10112: WB / Human, Mouse

Xinlei Hu et al.
Br J Pharmacol.,  (2021)

Decidual NR2F2-Expressing CD4 + T Cells Promote TH2 Transcriptional Program During Early Pregnancy.

ARG65350: WB / Mouse

Yikong Lin et al.
Front Immunol.,  (2021)

Curcumin attenuates renal ischemia reperfusion injury via JNK pathway with the involvement of p300/CBP-mediated histone acetylation

ARG10112: WB / Rat

Lu Yang et al.
Korean J Physiol Pharmacol.,  (2021)

MicroRNA-145 Delay Plaque Erosion by Down-Regulating TGFβr Ii and Suppressing Autophagy of Vascular Smooth Muscle Cells.

ARG65350: WB / Mouse

Yunjuan Jiao et al.
Preprint.,  (2021)

7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson's disease

ARG10112: WB / Mouse

Li Zuo et al.
Cell Death Discov.,  (2021)

Cardiac-Specific Gene TNNI3 as a Potential Oncogene for Kidney Cancer and Its Involvement in Wnt Signaling Pathway.

ARG10112: WB / Human

Weian Zhao et al.
Preprint.,  (2021)

Excessive fibroblast growth factor 23 promotes renal fibrosis in mice with type 2 cardiorenal syndrome.

ARG10112: WB / Mouse, Rat

Huixin Hao et al.
Aging (Albany NY).,  (2021)

Circ_0081572 inhibits the progression of periodontitis through regulating the miR-378h/RORA axis.

ARG10112: WB / Human

Jing Wang et al.
Arch Oral Biol.,  (2021)

Evaluation of Class IIa Histone Deacetylases Expression and In Vivo Epigenetic Imaging in a Transgenic Mouse Model of Alzheimer's Disease

ARG10112: WB / Human

Yi-An Chen et al.
Int J Mol Sci.,  (2021)

Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP.

ARG65350: WB / Mouse

Yajie Chen et al.
Proc Natl Acad Sci.,  (2021)

Increased expression levels of inflammatory cytokines and adhesion molecules in lipopolysaccharide‑induced acute inflammatory apoM‑/‑ mice

ARG10112: WB / Mouse

Yuanping Shi et al.
Mol Med Rep.,  (2020)

Codelivery of Anti-PD-1 Antibody and Paclitaxel with Matrix Metalloproteinase and pH Dual-Sensitive Micelles for Enhanced Tumor Chemoimmunotherapy.

ARG65350: WB, IHC-P / Mouse

Su Zhenwei et al.
Small.,  (2020)

ERK activation precedes Purkinje cell loss in mice with Spinocerebellar ataxia type 17.

ARG10112: WB / Mouse

Chia-Wei Lin et al.
Neurosci Lett.,  (2020)

CLC-3 and SOX2 regulate the cell cycle in DU145 cells

ARG65350: WB / Mouse

Jiahong Chen et al.
Oncol Lett.,  (2020)

Cardiac troponin I R193H mutant interacts with HDAC1 to repress phosphodiesterase 4D expression in cardiomyocytes

ARG10112: WB / Mouse

Weian Zhao et al.
Genes Dis.,  (2020)

miR-765 Impairs Pancreatic β-cell Function by Targeting PDX1 in type 2 Diabetes.

ARG65350: WB / Mouse

Li Zheng et al.
Preprint.,  (2020)

Study of isolation and characterization of extracellular vesicles in senescent tumor cells induced by chemotherapeutics.

ARG10112: WB / Human

Qi Zhou et al.
Chinese Journal of Immunology.,  (2020)

Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I.

ARG10112: WB / Human, Mouse

Geng Sun et al.
Eur J Med Chem.,  (2020)

Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development

ARG65350: WB / Mouse

Shanshan Wang et al.
Genes Dis .,  (2020)

High expression of FUSE binding protein 1 in breast cancer stimulates cell proliferation and diminishes drug sensitivity.

ARG65350: WB / Mouse

Liu Wei et al.
Int J Oncol.,  (2020)

SMARCB1 Promotes Ubiquitination and Degradation of NR4A3 via Direct Interaction Driven by ROS in Vascular Endothelial Cell Injury

ARG10112, ARG65350: WB / Human, Mouse, Rat

Bingzheng Lu et al.
Oxid Med Cell Longev.,  (2020)

Prokaryotic expression and immunogenicity analysis of Clostridium difficile binary toxin A.

ARG65350: WB / Mouse

Huang Yingfeng et al.
检验医学 (Laboratory Medicine),  (2020)

A single-component light sensor system allows highly tunable and direct activation of gene expression in bacterial cells.

ARG65350: WB / Mouse

Li Xie et al.
Nucleic Acids Res.,  (2020)

BCL7C suppresses ovarian cancer growth by inactivating mutant p53.

ARG65350: WB / Mouse

Canhua Huang et al.
J Mol Cell Biol.,  (2020)

Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells.

ARG10112: WB / Human

Li Sen et al.
J Exp Clin Cancer Res.,  (2019)

Genetic labeling reveals temporal and spatial expression pattern of D2 dopamine receptor in rat forebrain.

ARG10112: WB / Rat

Yu Qing et al.
Brain Struct Funct.,  (2019)

Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.

ARG65350: WB, IHC-P / Mouse

Chen Yajie et al.
Cell Death and Disease.,  (2019)

Down-regulation of HTR1A-modulated ACC activation contributes to stress-induced visceral hyperalgesia in rats.

ARG65350: WB / Mouse

Yi Lisha et al.
Neurogastroenterol Motil.,  (2019)

Effects of perfluorooctane on the retina as a short-term and small amounts remnant in rabbits.

ARG65350: IHC-P / Mouse

Li Qing-Chen et al.
Int J Ophthalmol.,  (2019)

SCM-198 protects endometrial stromal cells from oxidative damage through Bax/Bcl-2 and ERK signaling pathways.

ARG10112: WB / Human

Yunyun Li et al.
Acta Biochim Biophys Sin.,  (2019)

Epigenetic regulation of phosphodiesterase 4d in restrictive cardiomyopathy mice with cTnI mutations.

ARG10112: WB / Mouse

Zhao Weian et al.
Sci China Life Sci.,  (2019)

Icariin suppresses cell cycle transition and cell migration in ovarian cancer cells.

ARG65350: WB / Mouse

Wang Pengzhen et al.
Oncol Rep.,  (2019)

Treatment of diabetic mice with A Combination of Ketogenic Diet and Aerobic Exercise via modulations of PPARs gene programs.

ARG65350: WB / Mouse

Zhang Qiang et al.
PPAR Research.,  (2018)

AdipoRon prevents l-thyroxine or isoproterenol-induced cardiac hypertrophy through regulating the AMPK-related pathway.

ARG10112: WB / Rat

Hu Xinlei et al.
Acta Biochim Biophys Sin (Shanghai).,  (2018)

The effect of melatonin on cardio fibrosis in juvenile rats with pressure overload and deregulation of HDACs.

ARG10112: WB / Rat

Wu Yao et al.
Korean J Physiol Pharmacol.,  (2018)

Epigallocatechin-3 gallate prevents pressure overload-induced heart failure by up-regulating SERCA2a via histone acetylation modification in mice.

ARG10112: WB / Mouse

Liu Lifei et al.
PLoS One.,  (2018)

MIR4532 gene variant rs60432575 influences the expression of KCNJ11 and the sulfonylureas-stimulated insulin secretion.

ARG65350: WB / Mouse

Chen Zhang-Ren et al.
Endocrine.,  (2018)

Knockdown of LGALS12 inhibits porcine adipocyte adipogenesis via PKA-Erk1/2 signaling pathway

ARG65350: WB / Mouse

Wu Wenjing et al.
Acta Biochim Biophys Sin.,  (2018)

抗菌肽Sublancin增强小鼠获得性免疫的研究

ARG65350: ELISA / Mouse

张晓雅 et al.
动物营养学报,  (2018)

Hydrogen sulfide protects against endoplasmic reticulum stress and mitochondrial injury in nucleus pulposus cells and ameliorates intervertebral disc degeneration.

ARG10112: WB / Human

Xu D et al.
Pharmacol Res.,  (2017)

Cardiac Protection of Valsartan on Juvenile Rats with Heart Failure by Inhibiting Activity of CaMKII via Attenuating Phosphorylation

ARG10112: WB / Rat

Yao Wu et al.
BioMed Research International.,  (2017)

Checking transfer efficiency and equal loading via qualitative optical way in western blotting.

ARG10112: WB / Human

Gong JH et al.
Electrophoresis,  (2017)

Reciprocal regulation between O-GlcNAcylation and tribbles pseudokinase 2 (TRIB2) maintains transformative phenotypes in liver cancer cells.

ARG10112: WB / Human

Yao B et al.
Cell Signal.,  (2016)

Study on the inhibition of hyperthermic CO₂ pneumoperitoneum on the proliferation and migration of colon cancer cells and its mechanism.

ARG65350: WB / Mouse

Zhao J et al.
Oncol Rep.,  (2016)

Acute hyperglycemia suppresses left ventricular diastolic function and inhibits autophagic flux in mice under prohypertrophic stimulation.

ARG10112: WB / Mouse

Xie J et al.
Cardiovasc Diabetol.,  (2016)