ARG83037

Human MMP3 ELISA Kit

Human MMP3 ELISA Kit for ELISA and Human

Overview

Product Description ARG83037 Human MMP3 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human MMP3 in serum, plasma (heparin), ascites, urine and cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity Not cross-reacts with:
Human MMP1, MMP2, MMP7, MMP8, MMP9, MMP12, MMP13, TIMP 1.
Mouse MMP3, MMP9.
Rat MMP3, MMP9.
Target Name MMP3
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Protein Full Name Stromelysin-1
Sensitivity 15.6 pg/ml
Sample Type Serum, plasma (heparin), ascites, urine and cell culture supernatants.
Standard Range 31.3 - 2000 pg/ml
Sample Volume 100 µl
Precision Intra-Assay CV: less than 10%
Inter-Assay CV: less than 10%
Alternate Names MMP3, Matrix Metallopeptidase 3, STMY1, Matrix Metalloproteinase 3 (Stromelysin 1, Progelatinase), Stromelysin 1, EC 3.4.24.17, Transin 1, MMP 3, SL 1, STMY, Matrix Metalloproteinase 3, Proteoglycanase, Stromelysin 1, EC 3.4.24, CHDS6, STR1

Application Instructions

Assay Time ~ 4 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4314 Human MMP3

Swiss-port # P08254 Human Stromelysin-1

Gene Symbol MMP3
Gene Full Name Matrix Metallopeptidase 3
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Function Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9. [UniProt]
Cellular Localization Cytoplasm, Extracellular matrix, Nucleus, Secreted. [UniProt]
Highlight Related products:
MMP3 antibodies; MMP3 ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
PTM Disulfide bond, Zymogen. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG83037 Human MMP3 ELISA Kit standard curve image

    ARG83037 Human MMP3 ELISA Kit results of standard run with optical density reading at 450 nm

Title Download Link
ARG83037 Human MMP3 ELISA Kit User manual download icon Download