ARG83145
Human IGFBP2 ELISA Kit
Human IGFBP2 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83145 Human IGFBP2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IGFBP2 in Serum, Urine, Plasma, Cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | IGFBP2 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 15 pg/ml |
| Detection Range | 62.5 pg/ml - 4,000 pg/ml |
| Sample Type | Serum, Urine, Plasma and Cell culture supernatants. |
| Sample Volume | 100 μl |
| Precision | Intra-Assay CV: 6.0% Inter-Assay CV: 7.5% |
| Alternate Names | IBP2; IGF-BP53; IGF-binding protein 2; IGFBP-2 |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P18065 Human Insulin-like growth factor-binding protein 2 |
|---|---|
| Gene Symbol | IGFBP2 |
| Gene Full Name | Insulin Like Growth Factor Binding Protein 2 |
| Background | The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. |
| Function | Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. |
| Cellular Localization | Secreted. |
| PTM | O-glycosylated. |
Images (1) Click the Picture to Zoom In
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ARG83145 Human IGFBP2 ELISA Kit standard curve image
ARG83145 Human IGFBP2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83145 Human IGFBP2 ELISA Kit User manual |
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