ARG80903

Human BD2 / beta Defensin 2 ELISA kit

Human BD2 / beta Defensin 2 ELISA kit for ELISA and Human

Microbiology and Infectious Disease kit
publication_link Publication7

Overview

Product Description ARG80903 Human BD2 / beta Defensin 2 ELISA kit is a Enzyme Immunoassay kit for the quantification of Human BD2 / beta Defensin 2 in serum, plasma and cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity No significant cross-reactivity or interference with BD-1 (36 aa), BD-1 (47 aa), BD-3, BD-4.
Target Name BD2 / beta Defensin 2
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm
Sensitivity 4 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 7.8 - 500 pg/ml
Sample Volume 100 µl
Precision CV: less than10%
Alternate Names Beta-defensin 4; BNBD-4; BNDB-4; DEFB4; BNBD4

Application Instructions

Assay Time 4 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1673 Human DEFB4A

Swiss-port # O15263 Human Beta-defensin 4A

Gene Symbol DEFB4A
Gene Full Name defensin, beta 4A
Background Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta Defensin 2 is an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]
Function Beta Defensin 2 exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells (PubMed:20068036). [UniProt]
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Research Area Microbiology and Infectious Disease kit

Images (1) Click the Picture to Zoom In

  • ARG80903 Human BD2 / beta Defensin 2 ELISA kit standard curve image

    ARG80903 Human BD2 / beta Defensin 2 ELISA kit results of a typical standard run with optical density reading at 450 nm.

Specific References

Engineered Human Airway Mucosa for Modelling Respiratory Infections: Characterisation and Applications

ELISA / Human / Cell culture supernatants

Rinu Sivarajan et al.
,  (2023)

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β-defensin 2 synthesized by a cell-free protein synthesis system and encapsulated in liposomes inhibits adhesion of Porphyromonas gingivalis to oral epithelial cells

ELISA / Human / Cell culture supernatants

Yuka Hiroshima et al.
Odontology.,  (2023)

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Susceptibility of primary human airway epithelial cells to Bordetella pertussis adenylate cyclase toxin in two- and three-dimensional culture conditions

ELISA / Human / Airway mucosa

Maria Bianchi et al.
Innate Immun.,  (2022)

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GP IIb/IIIa-Mediated Platelet Activation and Its Modulation of the Immune Response of Monocytes Against Candida albicans

ELISA / Human / Cell culture supernatants

Lin Zheng et al.
Front Cell Infect Microbiol.,  (2022)

publication_link

 

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The level of antimicrobial peptides in gingival crevicular fluid and its correlation with periodontal clinical indexes in elderly patients with type 2 diabetic periodontitis

ELISA / Human / Body fluid

ZHANG Yameng et al.
Journal of Prevention and Treatment for Stomatological Diseases,  (2021)

publication_link

 

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Associations of ultrasound-based inflammation patterns with peripheral innate lymphoid cell populations, serum cytokines/chemokines, and treatment response to methotrexate in rheumatoid arthritis and spondyloarthritis.

ELISA / Human / Serum

Manami Kato et al.
PLoS One.,  (2021)

publication_link

 

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Galleria mellonella: A Novel Invertebrate Model to Distinguish Intestinal Symbionts From Pathobionts.

ELISA / Human

Lange A et al.
Front Immunol.,  (2018)

publication_link

 

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Title Download Link
ARG80903 Human BD-2 / beta Defensin-2 ELISA kit User's manual download icon Download