ARG80361

Human ANCA-P (MPO) ELISA Kit

Human ANCA-P (MPO) ELISA Kit for ELISA and Human

Cancer kit; Cell Biology and Cellular Response kit; Immune System kit; Metabolism kit

Overview

Product Description ARG80361 Human ANCA-P (MPO) ELISA Kit is an indirect solid phase enzyme immunoassay (ELISA) kit for the quantification of IgG class autoantibodies against myeloperoxidase (MPO) in human serum and plasma (EDTA, heparin, citrate).
Tested Reactivity Hu
Tested Application ELISA
Target Name ANCA-P
Conjugation HRP
Sensitivity 0.5 U/ml
Sample Type Serum and plasma (EDTA, heparin, citrate).
Standard Range 5 - 100 U/ml
Sample Volume 10 µl
Alternate Names MPO; Myeloperoxidase; EC 1.11.2.2

Application Instructions

Assay Time 30, 15, 15, 5 min (RT)

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4353 Human MPO

Swiss-port # P05164 Human Myeloperoxidase

Gene Symbol MPO
Gene Full Name myeloperoxidase
Background Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. [UniProt]
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Research Area Cancer kit; Cell Biology and Cellular Response kit; Immune System kit; Metabolism kit
Title Download Link
ARG80361 Human ANCA-P (MPO) ELISA Kit User's manual download icon Download