ARG30093
Hippocampal Neurogenesis Marker Antibody Duo (Prox1, Dcx)
Cell Biology and Cellular Response antibody; Controls and Markers antibody; Gene Regulation antibody; Neuroscience antibody
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG52403 | anti-Prox 1 antibody [5G10] | Mouse mAb | Hu, Ms, Rat, Chk | IHC | 50 μl |
| ARG52266 | anti-Doublecortin antibody [3 e1] | Mouse mAb | Hu, Ms, Rat, Bov | ICC/IF, IHC-Fr, WB | 50 μl |
Overview
| Product Description | Prox1 is a homeobox transcription factor that is essential for the generation of many organs during embryogenesis. It also plays a critical role in neurogenesis in the embryonic CNS and adult hippocampus. Prox1 postmitotically defines dentate gyrus cells by specifying granule cell identity over CA3 pyramidal cell fate in the hippocampus. It is used as a marker for intermediate progenitor cells. Doublecortin (DCX) is a microtubule-associated protein required for normal migration of neurons into the cerebral cortex. In the adult hippocampus, DCX is used as marker for immature neuronal cells in dentate gyrus. arigo’s ARG30093 Hippocampal Neurogenesis Marker Antibody Duo (Prox1, Dcx) is excellent for studying Hippocampal Neurogenesis in adult. Related news: "Pro-aging factor" tied to immune-related molecule |
|---|---|
| Target Name | Hippocampal Neurogenesis Marker |
| Alternate Names | Hippocampal Neurogenesis Marker antibody; Doublecortin antibody; Prox 1 antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Antibody Duo for Hippocampal Neurogenesis Marker (Prox1, Dcx) |
|---|---|
| Research Area | Cell Biology and Cellular Response antibody; Controls and Markers antibody; Gene Regulation antibody; Neuroscience antibody |
Images (5) Click the Picture to Zoom In
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ARG52266 anti-Doublecortin antibody [3 e1] ICC/IF image
Immunofluorescence: Cortical neuron-glial cell culture from E20 Rat stained with ARG52266 anti-Doublecortin antibody [3 e1] (red) at 1:1000 dilution, and costained with anti-MAP2 antibody (green) at 1:10000 dilution. DAPI (blue) for nuclear staining.
The Doublecortin antibody reveals strong cytoplasmic staining in a population of small developing neurons and their processes, while the MAP2 antibody stains dendrites and perikarya of mature neurons.
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ARG52266 anti-Doublecortin antibody [3 e1] WB image
Western Blot: postnatal day 3 rat brain lysate stained with Doublecortin antibody (ARG52266) showing specific immunolabeling of the ~35 & 45k doublecortin protein.
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ARG52403 anti-Prox 1 antibody [5G10] IHC-P image
Immunohistochemistry: Rat dentate gyrus showing specific immunolabeling of the prox1 protein stained with ARG52403 anti-Prox 1 antibody [5G10]
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ARG52266 anti-Doublecortin antibody [3 e1] WB image
Western blot: Adult Rat brain (negative control) and embryonic E20 Rat brain lysates stained with ARG52266 anti-Doublecortin antibody [3 e1] (green) at 1:1000 dilution.
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ARG52266 anti-Doublecortin antibody [3 e1] ICC/IF image
Immunofluorescence: cultured rat neurons showing strong cytoplasmic staining of doublecortin (green)(ARG52266) in developing neurons and GFAP (ARG52313) in red.
