ARG30343

GSDME-mediated Pyroptosis Antibody Panel

publication_link Publication4

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG42602 anti-GSDME / DFNA5 antibody Rabbit pAb Hu IP, WB 20 µl
ARG54938 anti-Caspase 3 antibody Rabbit pAb Hu, Ms, Rat ICC/IF, IHC, IP, WB 20 µl
ARG65863 anti-HMGB1 antibody [SQab1711] Mouse mAb Hu, Ms, Rat ELISA, FACS, ICC/IF, IHC-P, WB 20 µg

Overview

Target Name GSDME-mediated Pyroptosis

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Highlight Related products:
HMGB1 antibodies; HMGB1 ELISA Kits; HMGB1 Duos / Panels; HMGB1 recombinant proteins;

Related news:
HMGB1, a biomarker and therapeutic target in COVID-19
AMPK signaling regulates NLRP3 inflammation and pyroptosis

Images (16) Click the Picture to Zoom In

  • ARG54938 anti-Caspase 3 antibody WB image

    Western blot: 20 µg of Mouse brain and Rat brain lysates stained with ARG54938 anti-Caspase 3 antibody at 1:250 dilution.

  • ARG65863 anti-HMGB1 antibody [SQab1711] WB image

    Western blot: 20 µg of 22Rv1, DU145, Mouse liver and Rat liver lysates stained with ARG65863 anti-HMGB1 antibody [SQab1711] at 1:5000 dilution.

  • ARG54938 anti-Caspase 3 antibody ICC/IF image

    Immunofluorescence: NIH/3T3 cells stained with ARG54938 anti-Caspase 3 antibody at 1:100 dilution. Blue: DAPI for nuclear staining.

  • ARG65863 anti-HMGB1 antibody [SQab1711] ICC/IF image

    Immunofluorescence: 293T cells stained with ARG65863 anti-HMGB1 antibody [SQab1711] at 5 μg/ml dilution.

  • ARG65863 anti-HMGB1 antibody [SQab1711] FACS image

    Flow Cytometry: HuH-7 cell and HuH-7 shHMGB1 cell stained with ARG65863 anti-HMGB1 antibody [SQab1711] at 1 µg/ml dilution.

  • ARG54938 anti-Caspase 3 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human placenta stained with ARG54938 anti-Caspase 3 antibody at 1:100 dilution.

  • ARG65863 anti-HMGB1 antibody [SQab1711] IHC-P image

    Immunohistochemistry: Paraffin-embedded Human cervical cancer stained with ARG65863 anti-HMGB1 antibody [SQab1711] at 10 μg/ml dilution.

  • ARG65863 anti-HMGB1 antibody [SQab1711] WB image

    Western blot: 50 µg of 1) HuH-7 and 2) HuH-7 shHMGB1 cell lysates stained with ARG65863 anti-HMGB1 antibody [SQab1711] at 1:5000 dilution.

  • ARG42602 anti-GSDME / DFNA5 antibody WB image

    Western blot: HeLa cell lysate stained with ARG42602 anti-GSDME / DFNA5 antibody at 1:500 dilution.

  • ARG65863 anti-HMGB1 antibody [SQab1711] ELISA image

    ELISA: ARG65863 anti-HMGB1 antibody [SQab1711] at 1:5000 were used for detecting HMGB1. 5 µg/ml of HMGB1, HMGB2 and BSA proteins were coated onto ELISA plate.

  • ARG54938 anti-Caspase 3 antibody WB image

    Western blot: 20 µg of 293T, and HeLa cell lysates stained with ARG54938 anti-Caspase 3 antibody at 1:500 dilution.

  • ARG65863 anti-HMGB1 antibody [SQab1711] IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse liver stained with ARG65863 anti-HMGB1 antibody [SQab1711] at 10 μg/ml dilution.

  • ARG65863 anti-HMGB1 antibody [SQab1711] IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse kidney stained with ARG65863 anti-HMGB1 antibody [SQab1711] at 10 μg/ml dilution.

  • ARG65863 anti-HMGB1 antibody [SQab1711] IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat liver stained with ARG65863 anti-HMGB1 antibody [SQab1711] at 10 μg/ml dilution.

  • ARG65863 anti-HMGB1 antibody [SQab1711] WB image

    Western blot: 1) 50 ng of HMGB1 (Purified from E. coli) and 2) 100 ng of HMGB2 (Purified from E.coli) stained with ARG65863 anti-HMGB1 antibody [SQab1711] at 1:5000 dilution.

  • ARG65863 anti-HMGB1 antibody [SQab1711] WB image

    Western blot: 20 µg of 1) Mouse spleen and 2) Rat spleen lysates stained with ARG65863 anti-HMGB1 antibody [SQab1711] at 1:5000 dilution.

Specific References

Tumor cell-released autophagosomes (TRAPs) induce PD-L1-decorated NETs that suppress T-cell function to promote breast cancer pulmonary metastasis

ARG65863: FACS / Mouse

Xiaohe Zhou et al.
J Immunother Cancer.,  (2024)

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MiR-7-5p/KLF4 signaling inhibits stemness and radioresistance in colorectal cancer

ARG54938: WB / Human

Yuanyuan Shang et al.
Cell Death Discov.,  (2023)

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Human amniotic fluid mesenchymal stem cells attenuate pancreatic cancer cell proliferation and tumor growth in an orthotopic xenograft mouse model

ARG54938: WB / Human

Ying-Cheng Chen et al.
Stem Cell Res Ther,  (2022)

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Down-regulation of calreticulin promotes apoptosis in hepatic stellate cells.

ARG54938: WB / Human

Linyu Dai et al.
第三军医大学学报,  (2021)

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