ARG30300
Endothelial Cell Marker Antibody Duo (CD31, CD34)
Component
Cat No | Component Name | Host clonality | Reactivity | Application | Package |
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ARG52748 | anti-CD31 antibody | Rabbit pAb | Hu, Ms, Rat, Pig | ICC/IF, IHC-FoFr , IHC-Fr, IHC-P, WB | 50 μl |
ARG52756 | anti-CD34 antibody [QBEND/10] | Mouse mAb | Hu, Ms, NHuPrm, Rb | FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB | 50 μl |
Overview
Product Description | Cells expressing CD34 (CD34+ cell) are normally found in the umbilical cord and bone marrow as hematopoietic cells, a subset of mesenchymal stem cells, endothelial progenitor cells, endothelial cells of blood vessels. CD34 is one of the Endothelial Cell Differentiation Markers and Endothelial Progenitor Cell Markers. CD31 is normally found on endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, osteoclasts, neutrophils. In immunohistochemistry, CD31 is used primarily to demonstrate the presence of endothelial cells in histological tissue sections. This can help to evaluate the degree of tumour angiogenesis, which can imply a rapidly growing tumour. Malignant endothelial cells also commonly retain the antigen, so that CD31 immunohistochemistry can also be used to demonstrate both angiomas and angiosarcomas. ARG30300 Endothelial Cell Marker Duos, including antibodies react commonly used endothelial cell marker CD31 and CD34 for angiogenesis study. |
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Target Name | Endothelial Cell Marker |
Alternate Names | Endothelial Cell Marker antibody; CD31 antibody; CD34 antibody |
Properties
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
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Note | For laboratory research only, not for drug, diagnostic or other use. |
Images (12) Click the Picture to Zoom In
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ARG52756 anti-CD34 antibody [QBEND/10] ICC/IF image
Immunofluorescence: hCMEC/D3 cells stained with ARG52756 anti-CD34 antibody [QBEND/10].
From Lucie Y Li et al. Front Cell Neurosci. (2023), doi: 10.3389/fncel.2023.1077204, Fig. 3A & B.
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ARG52748 anti-CD31 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and Paraffin-embedded MDA-MB-231 (tumor xenograft study) stained with ARG52748 anti-CD31 antibody.
Antigen Retrieval Buffer: Bond Epitope Retrieval Solution. -
ARG52756 anti-CD34 antibody [QBEND/10] WB image
Western blot: 30 µg of mouse lung lysate stained with ARG52756 anti-CD34 antibody [QBEND/10] at 1:500 dilution.
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ARG52756 anti-CD34 antibody [QBEND/10] IHC-P image
Immunohistochemistry: Human Breast Ductal Carcinoma stained with CD34 (Endothelial Cell Marker) antibody [QBEnd/10] (ARG52756)
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ARG52756 anti-CD34 antibody [QBEND/10] IHC-P image
Immunohistochemistry: Human Cervical Squamous Cell carcinoma stained with CD34 (Endothelial Cell Marker) antibody [QBEnd/10] (ARG52756)
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ARG52756 anti-CD34 antibody [QBEND/10] IHC-P image
Immunohistochemistry: Human Colon stained with CD34 (Endothelial Cell Marker) antibody [QBEnd/10] (ARG52756)
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ARG52756 anti-CD34 antibody [QBEND/10] IHC-P image
Immunohistochemistry: Human Placenta stained with CD34 (Endothelial Cell Marker) antibody [QBEnd/10] (ARG52756)
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ARG52756 anti-CD34 antibody [QBEND/10] IHC-P image
Immunohistochemistry: Human Tonsil stained with CD34 (Endothelial Cell Marker) antibody [QBEnd/10] (ARG52756)
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ARG52748 anti-CD31 antibody WB image
Western blot: 30 µg of HUVEC lysate stained with ARG52748 anti-CD31 antibody at 1:500 dilution.
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ARG52748 anti-CD31 antibody IHC-P image
WB analysis of LLC xenograft mouse tumor tissue lysate stained with ARG52748 anti-CD31 antibody.
Reproduced under the Creative Commons license from Xu Fei et al. J Exp Clin Cancer Res., (2018) 37:207 Doi: 10.1186/s13046-018-0878-0, Fig. 7C.
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ARG52748 anti-CD31 antibody WB image
WB analysis of LLC xenograft mouse tumor tissue lysate stained with ARG52748 anti-CD31 antibody.
Reproduced under the Creative Commons license from Xu Fei et al. J Exp Clin Cancer Res., (2018) 37:207 Doi: 10.1186/s13046-018-0878-0, Fig. 7C.
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ARG52748 anti-CD31 antibody IHC image
Cryostat sections from Mouse Retinal stained with ARG52748 anti-CD31 antibody.
Reproduced under the Creative Commons license from Lin Chin-I et al. July/August 2019, 6(4) ENEURO.0391-18.2019 1–17, Doi: 10.1523/ENEURO.0391-18.2019, Fig. 4 A-C.
Specific References