ARG30300

Endothelial Cell Marker Antibody Duo (CD31, CD34)

publication_link Publication32

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG52748 anti-CD31 antibody Rabbit pAb Hu, Ms, Rat, Pig ICC/IF, IHC-FoFr , IHC-Fr, IHC-P, WB 50 μl
ARG52756 anti-CD34 antibody [QBEND/10] Mouse mAb Hu, Ms, NHuPrm, Rb FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB 50 μl

Overview

Product Description

Cells expressing CD34 (CD34+ cell) are normally found in the umbilical cord and bone marrow as hematopoietic cells, a subset of mesenchymal stem cells, endothelial progenitor cells, endothelial cells of blood vessels. CD34 is one of the Endothelial Cell Differentiation Markers and Endothelial Progenitor Cell Markers.

CD31 is normally found on endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, osteoclasts, neutrophils. In immunohistochemistry, CD31 is used primarily to demonstrate the presence of endothelial cells in histological tissue sections. This can help to evaluate the degree of tumour angiogenesis, which can imply a rapidly growing tumour. Malignant endothelial cells also commonly retain the antigen, so that CD31 immunohistochemistry can also be used to demonstrate both angiomas and angiosarcomas.

ARG30300 Endothelial Cell Marker Duos, including antibodies react commonly used endothelial cell marker CD31 and CD34 for angiogenesis study.

Target Name Endothelial Cell Marker
Alternate Names Endothelial Cell Marker antibody; CD31 antibody; CD34 antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Images (12) Click the Picture to Zoom In

  • ARG52756 anti-CD34 antibody [QBEND/10] ICC/IF image

    Immunofluorescence: hCMEC/D3 cells stained with ARG52756 anti-CD34 antibody [QBEND/10].

    From Lucie Y Li et al. Front Cell Neurosci. (2023), doi: 10.3389/fncel.2023.1077204, Fig. 3A & B.

  • ARG52748 anti-CD31 antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and Paraffin-embedded MDA-MB-231 (tumor xenograft study) stained with ARG52748 anti-CD31 antibody.
    Antigen Retrieval Buffer: Bond Epitope Retrieval Solution.

  • ARG52756 anti-CD34 antibody [QBEND/10] WB image

    Western blot: 30 µg of mouse lung lysate stained with ARG52756 anti-CD34 antibody [QBEND/10] at 1:500 dilution.

  • ARG52756 anti-CD34 antibody [QBEND/10] IHC-P image

    Immunohistochemistry: Human Breast Ductal Carcinoma stained with CD34 (Endothelial Cell Marker) antibody [QBEnd/10] (ARG52756)

  • ARG52756 anti-CD34 antibody [QBEND/10] IHC-P image

    Immunohistochemistry: Human Cervical Squamous Cell carcinoma stained with CD34 (Endothelial Cell Marker) antibody [QBEnd/10] (ARG52756)

  • ARG52756 anti-CD34 antibody [QBEND/10] IHC-P image

    Immunohistochemistry: Human Colon stained with CD34 (Endothelial Cell Marker) antibody [QBEnd/10] (ARG52756)

  • ARG52756 anti-CD34 antibody [QBEND/10] IHC-P image

    Immunohistochemistry: Human Placenta stained with CD34 (Endothelial Cell Marker) antibody [QBEnd/10] (ARG52756)

  • ARG52756 anti-CD34 antibody [QBEND/10] IHC-P image

    Immunohistochemistry: Human Tonsil stained with CD34 (Endothelial Cell Marker) antibody [QBEnd/10] (ARG52756)

  • ARG52748 anti-CD31 antibody WB image

    Western blot: 30 µg of HUVEC lysate stained with ARG52748 anti-CD31 antibody at 1:500 dilution.

  • ARG52748 anti-CD31 antibody IHC-P image

    WB analysis of LLC xenograft mouse tumor tissue lysate stained with ARG52748 anti-CD31 antibody.

    Reproduced under the Creative Commons license from Xu Fei et al. J Exp Clin Cancer Res., (2018) 37:207 Doi: 10.1186/s13046-018-0878-0, Fig. 7C.

  • ARG52748 anti-CD31 antibody WB image

    WB analysis of LLC xenograft mouse tumor tissue lysate stained with ARG52748 anti-CD31 antibody.

    Reproduced under the Creative Commons license from Xu Fei et al. J Exp Clin Cancer Res., (2018) 37:207 Doi: 10.1186/s13046-018-0878-0, Fig. 7C.

  • ARG52748 anti-CD31 antibody IHC image

    Cryostat sections from Mouse Retinal stained with ARG52748 anti-CD31 antibody.

    Reproduced under the Creative Commons license from Lin Chin-I et al. July/August 2019, 6(4) ENEURO.0391-18.2019 1–17, Doi: 10.1523/ENEURO.0391-18.2019, Fig. 4 A-C.

Specific References

circ-hnRNPU inhibits NONO-mediated c-Myc transactivation and mRNA stabilization essential for glycosylation and cancer progression

ARG52748: IHC-Fr / Human

Hongjun Li et al.
J Exp Clin Cancer Res.,  (2023)

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Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy

ARG52748: IHC-P / Mouse

Lili Liu et al.
Mater Today Bio.,  (2022)

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CT perfusion imaging can detect residual lung tumor early after radiofrequency ablation: a preliminary animal study on both tumoral and peri-tumoral region assessment

ARG52748: IHC-P / Rabbit

Zenghui Cheng et al.
J Thorac Dis.,  (2022)

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Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4

ARG52748: IHC-P / Human

Fan Yang et al.
J Cell Mol Med.,  (2022)

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Small Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhanced Proangiogenic Potential of Cardiac Fibroblasts via Angiopoietin-Like 4

ARG52748: WB / Human

Jiejie Li et al.
Stem Cells Int.,  (2022)

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Partial Reconstruction of Uterus Cervix in Rat by Decellularized Human Uterine Cervical Scaffold Combined with Adipose-Derived Stem Cells (ADSCs)

ARG52748: IHC-P / Mouse

Yuqi Li  et al.
J Immunol Res,  (2022)

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VEGF-C/VEGFR-3 axis protects against pressure-overload induced cardiac dysfunction through regulation of lymphangiogenesis.

ARG52748: IHC-P / Mouse

Qiu-Yue Lin et al.
Clin Transl Med.,  (2021)

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Exploring the mechanism of Bushenhuoxue formula acting on postmenopausal osteoporosis via network pharmacology and experimental validation.

ARG52748: IHC-P / Mouse

Chunhai Ke et al.
Preprint.,  (2021)

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Heterogeneous microenvironmental stiffness regulates pro-metastatic functions of breast cancer cells

ARG52748: IHC-P / Mouse

Chun Liu et al.
Acta Biomater.,  (2021)

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G6PD-NF-κB-HGF Signal in Gastric Cancer-Associated Mesenchymal Stem Cells Promotes the Proliferation and Metastasis of Gastric Cancer Cells by Upregulating the Expression of HK2

ARG52748: IHC-P / Mouse

Bin Chen et al.
Front Oncol,  (2021)

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pH and Glucose Dual-Responsive Injectable Hydrogels with Insulin and Fibroblasts as Bioactive Dressings for Diabetic Wound Healing

ARG52748: IHC-P / Rat

Lingling Zhao et al.
ACS Appl Mater Interfaces.,  (2021)

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Additive Antiproliferative and Antiangiogenic Effects of Metformin and Pemetrexed in a Non-Small-Cell Lung Cancer Xenograft Model.

ARG52748: IHC-P / Mouse

Jiun-Long Wang et al.
Front Cell Dev Biol.,  (2021)

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NIR-cleavable drug adducts of gold nanostars for overcoming multidrug-resistant tumors.

ARG52748: IHC-Fr / Mouse

Andrea C Del Valle et al.
Biomater Sci.,  (2020)

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Amygdalin Promotes Fracture Healing through TGF- β/Smad Signaling in Mesenchymal Stem Cells.

ARG52748: IHC-P / Mouse

Jun Ying et al.
Stem Cells Int.,  (2020)

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Platelet-rich plasma promotes bone formation, restrains adipogenesis and accelerates vascularization to relieve steroids-induced osteonecrosis of the femoral head.

ARG52748: IHC-P / Rat

Hui-Hui Xu et al.
Platelets.,  (2020)

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Bushenhuoxue formula accelerates fracture healing via upregulation of TGF-β/Smad2 signaling in mesenchymal progenitor cells.

ARG52748: IHC-P / Mouse

Hu Songfeng et al.
Phytomedicine.,  (2020)

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Peripheral Blood Stem Cell Therapy Does Not Improve Outcomes of Femoral Head Osteonecrosis With Cap-Shaped Separated Cartilage Defect.

ARG52748: IHC-P / Human

Ying Jun et al.
J Orthop Res.,  (2019)

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N-acetyl cysteine-loaded graphene oxide-collagen hybrid membrane for scarless wound healing.

ARG52748: IHC-P / Rat

Li Jialun et al.
Theranostics.,  (2019)

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Therapeutic targeting of circ-CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression.

ARG52748: IHC-P / Human

Huanhuan Li et al.
EMBO Mol Med.,  (2019)

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Blue Light Promotes Neurite Outgrowth of Retinal Explants in Postnatal ChR2 Mice.

ARG52748: IHC-Fr / Mouse

Lin Chin-I et al.
eNeuro.,  (2019)

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Polydopamine-coated gold nanostar for combined antitumor and antiangiogenic therapy in multidrug-resistant breast cancer.

ARG52748: IHC-Fr / Mouse

You You-Hong et al.
Nanotheranostics.,  (2019)

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Enhancing Microcirculation on Multitriggering Manner Facilitates Angiogenesis and Collagen Deposition on Wound Healing by Photoreleased NO from Hemin-Derivatized Colloids.

ARG52748: IHC-P / Mouse

Su Chia-Hao et al.
ACS Nano.,  (2019)

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Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling

ARG52748: IHC-P / Mouse

Xu Fei et al.
J Exp Clin Cancer Res.,  (2018)

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Stiffness Modification of Photopolymerizable Gelatin-Methacrylate Hydrogels Influences Endothelial Differentiation of Human Mesenchymal Stem Cells.

ARG52748: ICC/IF / Human

Lin Chih-Hsin et al.
J Tissue Eng Regen Med.,  (2018)

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Cis-acting circ-CTNNB1 promotes β-catenin signaling and cancer progression via DDX3-mediated transactivation of YY1.

ARG52748: IHC-P / Mouse

Yang Feng et al.
Cancer Res.,  (2018)

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Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes.

ARG52748: IHC-P / Mouse

Chen Yajun et al.
Cell Death Differ.,  (2018)

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Obesity enhances carcinogen 7, 12-Dimethylbenz [a] anthracene -induced tumorigenesis in vitro and in vivo.

ARG52748: IHC-P / Mouse

Hsieh Chia-Chien et al.
Food Chem Toxicol.,  (2017)

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Role of Angiogenesis in Chronic Radiation Proctitis: New Evidence Favoring Inhibition of Angiogenesis Ex Vivo.

ARG52756: IHC-P / Human

Wu Pei-Huang et al.
Dig Dis Sci.,  (2017)

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Administration of erythropoietin prevents bone loss in osteonecrosis of the femoral head in mice

ARG52748: IHC-P / Mouse

Taotao Xu et al.
Mol Med Rep.,  (2017)

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Injectable bioactive akermanite/alginate composite hydrogels for in situ skin tissue engineering

ARG52748: IHC-Fr / Mouse

Han Y et al.
J. Mater. Chem. B.,  (2017)

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Multifunctional Hydrogels Prepared by Dual Ion Cross-Linking for Chronic Wound Healing.

ARG52748: IHC-P / Mouse

Li Y et al.
ACS Appl Mater Interfaces.,  (2017)

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CO2 Delivery to Accelerate Incisional Wound Healing Following Single Irradiation of Near-Infrared Lamp on the Coordinated Colloids

ARG52748: IHC-P / Mouse

Wei-Peng Li et al.
ACS Nano. ,  (2017)

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